Pathological anatomy of lung vessels in COVID-19

نویسندگان

چکیده

Pathological anatomy of pulmonary vascular lesions plays a key role in understanding the patho-genesis and morphogenesis COVID-19. This review focuses on morphological features injury The virus is known to be capable causing not only cytopathic cell damage various organs tissues (type II pneumocytes, cardiomyocytes, neurons, epithelial cells gas-trointestinal tract) but also endotheliotropic that aggravates development course acute alveolar lungs. We studied literature microscopic changes vessel walls lung tissue for 2020–2022. discusses issues local or systemic lesions, morphologi-cal vessels over time, likelihood microangiopathy, vasculitis, endotheliitis COVID-19 patients. Particular attention paid possible mechanisms endotheliopathy patients its microthrombi genesis. speculate future, postmor-tem examination using histological, histochemical, immunohistochemical methods will clarify alterative inflammatory reparative processes blood walls, as well neoangiogenesis at different stages disease. Keywords: pathological anatomy, COVID-19, lungs, endotheliopathy, endotheliitis, microthrombus formation

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ژورنال

عنوان ژورنال: Klini?eskaâ i èksperimental?naâ morfologiâ

سال: 2022

ISSN: ['2226-5988', '2686-6749']

DOI: https://doi.org/10.31088/cem2022.11.2.6-12